Description
Aliases
SNRPA, U1 snRNP A, U1-A, U1A
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
P09012
Immunogen
Recombinant human U1 small nuclear ribonucleoprotein A protein (8-278AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Transcription
Literature
[1]”Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein.”Nelissen R.L.H., Sillekens P.T.G., Beijer R.P., Geurts van Kessel A.H.M., van Venrooij W.J.Gene 102:189-196(1991) [2]”cDNA cloniAdditional information
Size | 50μg, 100μg |
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