Description
Aliases
PCTP-like protein, PCTP-L, Antigen NY-CO-28, START domain-containing protein 10, StARD10, Serologically defined colon cancer antigen 28, StAR-related lipid transfer protein 10, STARD10, SDCCAG28, CGI-52
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9Y365
Immunogen
Recombinant human PCTP-like protein (1-291AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes.
Isotype
IgG
Conjugate
FITC
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]”StarD10, a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein.”Olayioye M.A., Vehring S., Muller P., Herrmann A., Schiller J., Thiele C., Lindeman G.J., Visvader J.E., Pomorski T.J. Biol. Chem. 280:27436-27442(2005). [2]”Phosphorylation of StarD10 on serine 284 by casein kinase II modulates its lipid transfer activity.”Olayioye M.A., Buchholz M., Schmid S., Schoffler P., Hoffmann P., Pomorski T.J. Biol. Chem. 282:22492-22498(2007). [3]”A quantitative atlas of mitotic phosphorylation.”Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).Additional information
| Size | 50μg, 100μg |
|---|
