NCBI Protein: NP_003144.3
Peptide sequence around phosphorylation site of Tyrosine 641 (R-G-Y(p)-V-P) derived from Human STAT6.
WB IHC Recommended dilution: Predicted MW: 110kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,
Background / Function
Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.Nelms K, et al. (1999) Annu Rev Immunol. 17:701-738.Malabarba M G, et al. (1996) Biochem. J. 319:865-872.Hou J, et al. (1994) Science. 265:1701-1706.Quelle F W, et al. (1995) Mol Cell Biol. 15: 3336-3343.Takeda K, et al. (1996) Nature. 380: 627-630.
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.