Stathmin1(Phospho-Ser25) Antibody

$454.00

Cat. No.: 38807 Categories: ,

Description

Aliases

STMN1; STN1; stathmin

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: P16949
NCBI Protein: NP_001138926.

Immunogen

Peptide sequence around phosphorylation site of serine 25 (I-L-S(p)-P-R) derived from Human Stathmin 1.

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IHC Recommended dilution: Predicted MW: 19kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,

Background / Function

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear Boehm M, et al. (2002) EMBO J 21(13): 3390-3401.Vadlamudi RK, et al. (2005) Mol Cell Biol 25(9): 3726-3736.Zilfou JT, et al. (2001) Mol Cell Biol 21(12): 3974-3985.Biernat J, et al. (2002) Mol Biol Cell 13(11): 4013-4028.

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser25

Additional information

Size

100?l

Certificate of Analysis