Stathmin1(Phospho-Ser38) Antibody

$454.00

Cat. No.: 38808 Categories: ,

Description

Aliases

STMN1; STN1; stathmin

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: P16949
NCBI Protein: NP_001138926.

Immunogen

Peptide sequence around phosphorylation site of serine 38 (P-L-S(p)-P-P) derived from Human Stathmin 1.

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IHC Recommended dilution: Predicted MW: 19kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,

Background / Function

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear Wang KK, et al. (1991) Biochem J 279(Pt 2): 537-544.Sekimoto T, et al. (2004) EMBO J 23(9): 1934-1942.Doye V, et al. (1992) Biochem J 287(Pt 2): 549-554.Larsson N, et al. (1999) Mol Cell Biol 19(3): 2242-2250.

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser38

Additional information

Size

100?l

Certificate of Analysis