Description
Aliases
Dehydroepiandrosterone sulfotransferase, DHEA-ST, Hydroxysteroid Sulfotransferase, HST, ST2, ST2A3, Sulfotransferase 2A1, ST2A1, SULT2A1, HST, STD
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q06520
Immunogen
Recombinant human Bile salt sulfotransferase protein (1-145AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC;Recommended dilution:IHC:1:20-1:200
Background / Function
Sulfotransferase that utilizes 3′-phospho-5′-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
Literature
[1]Identifying androsterone (ADT) as a cognate substrate for human dehydroepiandrosterone sulfotransferase (DHEA-ST) important for steroid homeostasis: structure of the enzyme-ADT complex.”Chang H.J., Shi R., Rehse P., Lin S.X.J. Biol. Chem. 279:2689-2696(2004). [2]Crystal structure of human dehydroepiandrosterone sulphotransferase in complex with substrate.” Rehse P.H., Zhou M., Lin S.X.Biochem. J. 364:165-171(2002). [3]Crystal structure of SULT2A3, human hydroxysteroid sulfotransferase.”Pedersen L.C., Petrotchenko E.V., Negishi M.FEBS Lett. 475:61-64(2000).Additional information
| Size | 50μl, 100μl |
|---|
