Description
Aliases
Beta ig-h3, Kerato-epithelin, RGD-containing collagen-associated protein, RGD-CAP, TGFBI, BIGH3
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q15582
Immunogen
Recombinant human Transforming growth factor-beta-induced protein ig-h3 protein (30-250AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC;Recommended dilution:IHC:1:20-1:200
Background / Function
Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen Affinity Purified
Literature
[1]Expanding the mutational spectrum in TGFBI-linked corneal dystrophies: identification of a novel and unusual mutation (Val113Ile) in a family with granular dystrophy.”Zenteno J.C., Ramirez-Miranda A., Santacruz-Valdes C., Suarez-Sanchez R.Mol. Vis. 12:331-335(2006). [2]Unilateral lattice corneal dystrophy associated with the novel His572del mutation in the TGFBI gene.” Aldave A.J., Rayner S.A., Kim B.T., Prechanond A., Yellore V.S.Mol. Vis. 12:142-146(2006). [3]A novel H572R mutation in the transforming growth factor-beta-induced gene in a Thai family with lattice corneal dystrophy type I.”Atchaneeyasakul L.-O., Appukuttan B., Pingsuthiwong S., Yenchitsomanus P.-T., Trinavarat A., Srisawat C.Jpn. J. Ophthalmol. 50:403-408(2006).Additional information
Size | 50μl, 100μl |
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