TGFBI Antibody

$138.92$232.63

SKU: 57938 Categories: ,

Description

Aliases

Beta ig-h3, Kerato-epithelin, RGD-containing collagen-associated protein, RGD-CAP, TGFBI, BIGH3

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

Q15582

Immunogen

Recombinant human Transforming growth factor-beta-induced protein ig-h3 protein (30-250AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, IHC;Recommended dilution:IHC:1:20-1:200

Background / Function

Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antigen Affinity Purified

Literature

[1]Expanding the mutational spectrum in TGFBI-linked corneal dystrophies: identification of a novel and unusual mutation (Val113Ile) in a family with granular dystrophy.”Zenteno J.C., Ramirez-Miranda A., Santacruz-Valdes C., Suarez-Sanchez R.Mol. Vis. 12:331-335(2006). [2]Unilateral lattice corneal dystrophy associated with the novel His572del mutation in the TGFBI gene.” Aldave A.J., Rayner S.A., Kim B.T., Prechanond A., Yellore V.S.Mol. Vis. 12:142-146(2006). [3]A novel H572R mutation in the transforming growth factor-beta-induced gene in a Thai family with lattice corneal dystrophy type I.”Atchaneeyasakul L.-O., Appukuttan B., Pingsuthiwong S., Yenchitsomanus P.-T., Trinavarat A., Srisawat C.Jpn. J. Ophthalmol. 50:403-408(2006).

Additional information

Size

50μl, 100μl

Certificate of Analysis