B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40; TNR5; tumor necrosis factor receptor superfamily member 5
Peptide sequence around phosphorylation site of threonine 254 (Q-E-T(p)-L-H) derived from Human TNFRSF5.
WB Recommended dilution: Western blotting: 1:500~1:3000,
Background / Function
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.