Description
Aliases
B-cell surface antigen CD40; Bp50; CD40 antigen; CD40L receptor; CDw40; TNR5; tumor necrosis factor receptor superfamily member 5
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#:P25942;
NCBI Gene#:958
Immunogen
Peptide sequence around phosphorylation site of threonine 254 (Q-E-T(p)-L-H) derived from Human TNFRSF5.
Raised In
Rabbit
Species Reactivity
Human Mouse
Tested Applications
WB Recommended dilution: Western blotting: 1:500~1:3000,
Background / Function
Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Thr254
Additional information
| Size | 100?l |
|---|
