Description
Aliases
Antigen NY-CO-38/NY-CO-37, Autoimmune enteropathy-related antigen AIE-75, Protein PDZ-73, Renal carcinoma antigen NY-REN-3, Usher syndrome type-1C protein, USH1C, AIE75
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9Y6N9
Immunogen
Recombinant human Harmonin protein (1-533AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Neuroscience
Literature
[1]”The structure of the harmonin/sans complex reveals an unexpected interaction mode of the two Usher syndrome proteins.”Yan J., Pan L., Chen X., Wu L., Zhang M.Proc. Natl. Acad. Sci. U.S.A. 107:4040-4045(2010).Additional information
| Size | 50μg, 100μg |
|---|
