ZNRF3 Antibody, Biotin conjugated

$231.52$415.64

SKU: 57305 Categories: ,

Description

Aliases

E3 ubiquitin-protein ligase ZNRF3, RING finger protein 203, Zinc/RING finger protein 3, ZNRF3, KIAA1133, RNF203

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

Q9ULT6

Immunogen

Recombinant human E3 ubiquitin-protein ligase ZNRF3 protein (56-219AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

>95%,Protein G purified

Additional information

Size

50μg, 100μg

Certificate of Analysis