H4; H4/n; H4F2; H4FN; FO108; HIST2H4
Gene ID: 8290 Swiss Prot: Q16695
A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4
Human Mouse Rat
WB IF IP ChIP Recommended dilution: WB 1:500 – 1:2000
CHIP 1:50 – 1:100
Background / Function
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antigen Affinity Purified