Histone H4K20me3 Polyclonal Antibody

$487.00

Cat. No.: 39208 Categories: ,

Description

Aliases

H4; H4/n; H4F2; H4FN; FO108; HIST2H4

Antibody Type

Polyclonal Antibody

Uniprot ID

Gene ID: 8290 Swiss Prot: Q16695

Immunogen

A synthetic methylated peptide corresponding to residues surrounding K20 of human histone H4

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IF IP ChIP Recommended dilution: WB 1:500 – 1:2000

IF 1:50 – 1:200
IP 1:50 – 1:200

CHIP 1:50 – 1:100

Background / Function

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.

Conjugate

Unconjugated

Storage Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antigen Affinity Purified

Modification

K20me3

Additional information

Size

100?l

Certificate of Analysis