Description
Aliases
Ubiquitin-protein ligase E3C, HECT-type ubiquitin transferase E3C, HectH2, UBE3C, KIAA0010, KIAA10
Antibody Type
Polyclonal
Species
Human
Uniprot ID
Q15386
Immunogen
Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA
Background / Function
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either ‘Lys-29’- or ‘Lys-48’-linked polyubiquitin chains. Has preference for ‘Lys-48’ linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
>95%,Protein G purified
Modification
Ubiquitin-protein ligase E3C
Additional information
| Size | 50μg, 100μg |
|---|
