ADM Antibody, Biotin conjugated

$210.00$377.00

Cat. No.: 39718 Categories: ,

Description

Aliases

ProAM N-terminal 20 peptide, PAMP, ProAM-N20

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P35318

Immunogen

Recombinant human ADM protein (45-92AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Neuroscience

Literature

[1]”NMR conformational analysis of proadrenomedullin N-terminal 20 peptide, a proangiogenic factor involved in tumor growth.”Lucyk S., Taha H., Yamamoto H., Miskolzie M., Kotovych G.Biopolymers 81:295-308(2006).

Additional information

Size

50μg, 100μg

Certificate of Analysis