ALDOA Antibody, HRP conjugated

$210.00$377.00

Description

Aliases

ALDOA, ALDA, Lung cancer antigen NY-LU-1, Muscle-type aldolase

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P04075

Immunogen

Recombinant human Fructose-bisphosphate aldolase A protein (2-364AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein .Defects in ALDOA are the cause of glycogen storage disease type 12 (GSD12) [MIM:611881]; also known as red cell aldolase deficiency. A metabolic disorder associated with increased hepatic glycogen and hemolytic anemia. It may lead to myopathy with exercise intolerance and rhabdomyolysis.Belongs to the class I fructose-bisphosphate aldolase family.

Isotype

IgG

Conjugate

HRP

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Fructose-bisphosphate aldolase A protein

Research

Metabolism

Literature

[1]”Nucleotide sequence of a cDNA clone for human aldolase: a messenger RNA in the liver.” Sakakibara M., Mukai T., Hori K. Biochem. Biophys. Res. Commun. 131:413-420(1985) [2]”A new human species of aldolase A mRNA from fibroblasts.” Izzo P., Costanz

Additional information

Size

50μg, 100μg

Certificate of Analysis