ALDOA, ALDA, Lung cancer antigen NY-LU-1, Muscle-type aldolase
Recombinant human Fructose-bisphosphate aldolase A protein (2-364AA)
ELISA;Not yet tested in other applications.
Background / Function
Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein .Defects in ALDOA are the cause of glycogen storage disease type 12 (GSD12) [MIM:611881]; also known as red cell aldolase deficiency. A metabolic disorder associated with increased hepatic glycogen and hemolytic anemia. It may lead to myopathy with exercise intolerance and rhabdomyolysis.Belongs to the class I fructose-bisphosphate aldolase family.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Caprylic Acid Ammonium Sulfate Precipitation purified
Fructose-bisphosphate aldolase A protein
Literature”Nucleotide sequence of a cDNA clone for human aldolase: a messenger RNA in the liver.” Sakakibara M., Mukai T., Hori K. Biochem. Biophys. Res. Commun. 131:413-420(1985) ”A new human species of aldolase A mRNA from fibroblasts.” Izzo P., Costanz