Description
Aliases
Downstream of tyrosine kinase 5 Insulin receptor substrate 6 DOK5 C20orf180
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9P104
Immunogen
Recombinant human Docking protein 5 protein (1-198AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Research
Signal Transduction
Literature
[1]Luo W.Q., Chen J.H., Huang X.W., Zhou Y., Zhou H.J., Hu S.N., Yuan J.G.Submitted (MAR-1999) [2]"DOK4 and DOK5: new Dok-related genes expressed in human T cells."Favre C., Gerard A., Clauzier E., Pontarotti P., Olive D., Nunes J.A.Genes ImAdditional information
Size | 50μg, 100μg |
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