Description
Aliases
activator protein 1; AP-1; C-FOS; cellular oncogene c-fos; Cellular oncogene fos; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FOS; G0/G1 switch regulatory protein 7; G0S7; Proto-o
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot#: P01100
Immunogen
A synthesized peptide derived from human Fos
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IHC Recommended dilution: WB 1:500-1:2000, IHC 1:50-1:200
Background / Function
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Conjugate
Unconjugated
Storage Buffer
Rabbit IgG in phosphate buffered saline , pH7.4, 150mM NaCl, 0.02% sodium azide and50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Affinity-chromatography
Additional information
| Size | 100μl |
|---|
