Recombinant mouse Guanylate cyclase activator 2B protein (22-106AA)
ELISA;Not yet tested in other applications.
Background / Function
Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Caprylic Acid Ammonium Sulfate Precipitation purified
LiteratureUroguanylin and guanylin: distinct but overlapping patterns of messenger RNA expression in mouse intestine. Whitaker T.L., Witte D.P., Scott M.C., Cohen M.B. Gastroenterology 113:1000-1006(1997). Sanford L.P., Cohen M.B.Submitted (FEB-2000).