Pro-neuregulin-2, membrane-bound isoform, Pro-NRG2Cleaved into the following chain:Neuregulin-2, NRG-2, NRG2, NTAK, Divergent of neuregulin-1, DON-1, Neural- and thymus-derived activator for ERBB kinases, NTAK
Recombinant human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA)
ELISA;Not yet tested in other applications.
Background / Function
Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Caprylic Acid Ammonium Sulfate Precipitation purified