RAP1A Antibody, FITC conjugated

$210.00$377.00

Cat. No.: 44302 Categories: ,

Description

Aliases

Ras-related protein Rap-1A, RAP1A, KREV1, C21KG, G-22K, GTP-binding protein smg p21A, Ras-related protein Krev-1

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P62834

Immunogen

Recombinant human Ras-related protein Rap-1A protein (1-181AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.

Isotype

IgG

Conjugate

FITC

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Additional information

Size

50μg, 100μg

Certificate of Analysis