Reg3g Antibody

$210.00$377.00

Cat. No.: 44384 Categories: ,

Description

Aliases

REG-3-gamma, Pancreatitis-associated protein 3, Regenerating islet-derived protein III-gamma, Reg III-gamma, Pap3, Reg3g

Antibody Type

Polyclonal Antibody

Species

Rat

Uniprot ID

P42854

Immunogen

Recombinant rat Regenerating islet-derived protein 3-gamma protein (2-110AA)

Raised In

Rabbit

Species Reactivity

Rat,mouse

Tested Applications

ELISA, WB;Not yet tested in other applications.

Background / Function

Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regulates keratinocyte proliferation and differentiation after skin injury (By similarity).

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Regenerating islet-derived protein 3-gamma

Literature

[1]”Reg3G gene expression in regenerating skeletal muscle and corresponding nerve.” Klasan G.S., Ivanac D., Erzen D.J., Picard A., Takasawa S., Peharec S., Arbanas J., Girotto D., Jerkovic R. Muscle Nerve 49:61-68(2014). [2]”Cloning, expression and chromosomal localization of the rat pancreatitis-associated protein III gene.” Dusetti N.J., Frigerio J.-M., Szpirer C., Dagorn J.-C., Iovanna J.L. Biochem. J. 307:9-16(1995). [3]”The pancreatitis associated protein III (PAP III), a new member of the PAP gene family.” Frigerio J.-M., Dusetti N.J., Garrido P., Dagorn J.-C., Iovanna J.L. Biochim. Biophys. Acta 1216:329-331(1993).

Additional information

Size

50μg, 100μg

Certificate of Analysis