RELN Antibody, FITC conjugated

$210.00$377.00

Cat. No.: 44390 Categories: ,

Description

Aliases

RELN

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P78509

Immunogen

Recombinant Human Reelin protein (26-254AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation

Isotype

IgG

Conjugate

FITC

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Cell Adhesion

Literature

[1]The human reelin gene: isolation, sequencing, and mapping on chromosome 7.DeSilva U., D’Arcangelo G., Braden V.V., Chen J., Miao G.G., Curran T., Green E.D.Genome Res. 7:157-164(1997) [2] The DNA sequence of human chromosome 7.Hillier L.W., Fulton R.

Additional information

Size

50μg, 100μg

Certificate of Analysis