Caspase-3, 7 Substrate (Ac-DEVD-pNA) [1mM], Colorimetric


Cat. No.: 10052 Categories: ,


Caspase-3, 7 Substrate (Ac-DEVD-pNA) [1mM], Colorimetric


General description

This product is a ready-to-use colorimetric substrate for CPP32/Caspase-3 and related caspases that recognize the amino acid sequence DEVD. The sequence DEVD is based on Caspase-3 cleavage site in poly (ADP-ribose) polymerase (PARP). CPP32 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l = 400 nm) after cleavage from the peptide substrate DEVD-pNA, using a spectrophotometer or multi-well plate reader.


Synonyms:                     Ac-DEVD-pNA, Caspase-3 Substrate, Colorimetric

Peptide Sequence:       Ac-Asp-Glu-Val-Asp-pNA

Appearance:                  Liquid

Formulation:                  DMSO (4 mM)

Molecular Formula:      C₂₆H₃₄N₆O₁₃

Molecular Weight:         638.58

InChi Key:                       GGXRLUDNGFFUKI-UHFFFAOYSA-N

PubChem CID:               4329

Handling:                        Protect from light and moisture

Storage temp.:                -20°C


Additional information



Certificate of Analysis