CTNNB1 Antibody, FITC conjugated

$210.00$377.00

Cat. No.: 39838 Categories: ,

Description

Aliases

CTNNB1, CTNNB, OK/SW-cl.35, PRO2286, Beta-catenin

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P35222

Immunogen

Recombinant human Catenin beta-1 protein (2-781AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Involved in the regulation of cell adhesion. The majority of beta-catenin is localized to the cell membrane and is part of E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton. Involved in signal transduction through the Wnt pathway. Nuclear beta-catenin it involved in transcriptional regulation by association with transcription factors of the TCF/LEF family.

Isotype

IgG

Conjugate

FITC

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Catenin beta-1 protein

Research

Cell Adhesion

Literature

[1]”E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.” Huelsken J., Birchmeier W., Behrens J.J. Cell Biol. 127:2061-2069(1994)

Additional information

Size

50μg, 100μg

Certificate of Analysis