EPHX2 Antibody, HRP conjugated

$210.00$377.00

Description

Aliases

Bifunctional epoxide hydrolase 2, Epoxide hydratase, Soluble epoxide hydrolase, SEH, Lipid-phosphate phosphatase, EPHX2

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P34913

Immunogen

Recombinant Human Bifunctional epoxide hydrolase 2 (1-555AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate.

Isotype

IgG

Conjugate

HRP

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Literature

[1]”Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms.”Sandberg M., Hassett C., Adman E.T., Meijer J., Omiecinski C.J.J. Biol. Chem. 275:28873-28881(2000). [2]”Cloning of human full-length CDSs in BD Creator(TM) system donor vector.” Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A. Submitted (MAY-2003). [3]”Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. Sugano S.Nat. Genet. 36:40-45(2004).

Additional information

Size

50μg, 100μg

Certificate of Analysis