Description
Aliases
Cytokine-responsive protein CR6, DNA damage-inducible transcript 2 protein, CR6, DDIT2, GADD45G
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
O95257
Immunogen
Recombinant human Growth arrest and DNA damage-inducible protein GADD45 gamma protein (1-159AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA;Not yet tested in other applications.
Background / Function
Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.
Isotype
IgG
Conjugate
Biotin
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Modification
Growth arrest and DNA damage-inducible protein GADD45 gamma
Literature
[1]”Crystal structure of human Gadd45gamma reveals an active dimer.” Zhang W., Fu S., Liu X., Zhao X., Zhang W., Peng W., Wu C., Li Y., Li X., Bartlam M., Zeng Z.H., Zhan Q., Rao Z. Protein Cell 2:814-826(2011). [2]”CR6-interacting factor 1 interacts with Gadd45 family proteins and modulates the cell cycle.” Chung H.K., Yi Y.-W., Jung N.-C., Kim D., Suh J.M., Kim H., Park K.C., Song J.H., Kim D.W., Hwang E.S., Yoon S.-H., Bae Y.-S., Kim J.M., Bae I., Shong M. J. Biol. Chem. 278:28079-28088(2003). [3]”The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Team Genome Res. 14:2121-2127(2004).Additional information
| Size | 50μg, 100μg |
|---|
