N-Methyl-D-Aspartic Acid is an excitotoxic amino acid. It is a prototypic agonist at the NMDA-type glutamate receptor that regulates ion channels, and it is important in long-term potentiation, ischemia, and epilepsy. N-Methyl-D-aspartic acid plays a crucial role in release of luteinizing hormone and prolactin in the pituitary gland and gonadotropin releasing hormone in the hypothalamus. It acts as a specific agonist for NMDA type glutamate receptors.
(R)-2-(Methylamino)succinic acid, NMDA