KS6A1; MAPKAP-K1a; RPS6KA1; RSK-1; RSK1
NCBI Protein: NP_001006666.
Peptide sequence around phosphorylation site of serine 352 (R-D-S(p)-P-G) derived from Human p90RSK.
Human Mouse Rat
WB Recommended dilution: Predicted MW: 90kd, Western blotting: 1:500~1:1000
Background / Function
Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. Silverman E, et al. Mol Cell Biol. 2004 Dec; 24(24): 10573-10583. Itoh S, et al. J Biol Chem 2005 Jun 24; 280(25): 24135-24142 Eisenmann KM, et al. Cancer Res 2003 Dec 01; 63(23): 8330-7
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.