p90RSK(Phospho-Ser352) Antibody

$454.00

Cat. No.: 38768 Categories: ,

Description

Aliases

KS6A1; MAPKAP-K1a; RPS6KA1; RSK-1; RSK1

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: Q15418
NCBI Protein: NP_001006666.

Immunogen

Peptide sequence around phosphorylation site of serine 352 (R-D-S(p)-P-G) derived from Human p90RSK.

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB Recommended dilution: Predicted MW: 90kd, Western blotting: 1:500~1:1000

Background / Function

Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB. Silverman E, et al. Mol Cell Biol. 2004 Dec; 24(24): 10573-10583. Itoh S, et al. J Biol Chem 2005 Jun 24; 280(25): 24135-24142 Eisenmann KM, et al. Cancer Res 2003 Dec 01; 63(23): 8330-7

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser352

Additional information

Size

100?l

Certificate of Analysis