PKD/PKCm(Phospho-Ser738) Antibody

$454.00

Cat. No.: 38752 Categories: ,

Description

Aliases

KPCD1; PKC-mu; PKCM; PKD; PRKCM

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: Q15139
NCBI Protein: NP_002733.2

Immunogen

Peptide sequence around phosphorylation site of serine 738 (E-K-S(p)-F-R) derived from Human PKD/PKCm.

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IF Recommended dilution: Predicted MW: 115kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Background / Function

Converts transient diacylglycerol. (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.Storz P, et al. Mol Cell Biol. 2004 Apr; 24(7): 2614-2626.Storz P, et al. Mol Cell Biol. 2005 Oct; 25(19): 8520-8530.Zhang W, et al. J Biol Chem 2005 May 13; 280(19): 19036-19044

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser738

Additional information

Size

100?l

Certificate of Analysis