Description
Aliases
KPCD1; PKC-mu; PKCM; PKD; PRKCM
Antibody Type
Polyclonal Antibody
Uniprot ID
Swiss-Prot: Q15139
NCBI Protein: NP_002733.2
Immunogen
Peptide sequence around phosphorylation site of serine 738 (E-K-S(p)-F-R) derived from Human PKD/PKCm.
Raised In
Rabbit
Species Reactivity
Human Mouse Rat
Tested Applications
WB IF Recommended dilution: Predicted MW: 115kd, Western blotting: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Background / Function
Converts transient diacylglycerol. (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.Storz P, et al. Mol Cell Biol. 2004 Apr; 24(7): 2614-2626.Storz P, et al. Mol Cell Biol. 2005 Oct; 25(19): 8520-8530.Zhang W, et al. J Biol Chem 2005 May 13; 280(19): 19036-19044
Conjugate
Unconjugated
Storage Buffer
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form
liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Ser738
Additional information
| Size | 100?l |
|---|
