QPCT Antibody, HRP conjugated

$210.00$377.00

Description

Aliases

Glutaminyl cyclase Glutaminyl-tRNA cyclotransferase Glutamyl cyclase QPCT

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

Q16769

Immunogen

Recombinant human Glutaminyl-peptide cyclotransferase protein (29-361AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Isotype

IgG

Conjugate

HRP

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Neuroscience

Literature

[1]Molecular cloning, sequence analysis and expression of human pituitary glutaminyl cyclase.Song I., Chuang C.Z., Bateman R.C. Jr.J. Mol. Endocrinol. 13:77-86(1994) [2]Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Su

Additional information

Size

50μg, 100μg

Certificate of Analysis