Description
Aliases
activating transcription factor 2
Antibody Type
Polyclonal Antibody
Uniprot ID
P15336
Immunogen
Fusion protein of human ATF2
Raised In
Rabbit
Species Reactivity
Human, Mouse, Rat
Tested Applications
ELISA: 1:2000-1:5000; IHC: 1:25-1:100
Background / Function
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen affinity purification
Additional information
| Size | 50μl, 100μl |
|---|
