Description
Aliases
beta-site APP-cleaving enzyme 1
Antibody Type
Polyclonal Antibody
Uniprot ID
P56817
Immunogen
Fusion protein of human BACE1
Raised In
Rabbit
Species Reactivity
Human, Mouse, Rat
Tested Applications
ELISA: 1:1000-1:2000; IHC: 1:15-1:50
Background / Function
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer’s disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Antigen affinity purification
Additional information
| Size | 50μl, 100μl |
|---|
