RCVRN Antibody, HRP conjugated

$210.00$377.00

Description

Aliases

Cancer-associated retinopathy protein, RCV1, RCVRN

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P35243

Immunogen

Recombinant human Recoverin protein (2-200AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Seems to be implicated in the pathway from retinal rod guanylate cyclase to rhodopsin. May be involved in the inhibition of the phosphorylation of rhodopsin in a calcium-dependent manner. The calcium-bound recoverin prolongs the photoresponse.

Isotype

IgG

Conjugate

HRP

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Modification

Recoverin

Literature

[1]”Crystal structure of human recoverin at 2.2 A resolution.” RIKEN structural genomics initiative (RSGI) Submitted (FEB-2007). [2]”A photoreceptor calcium binding protein is recognized by autoantibodies obtained from patients with cancer-associated retinopathy.” Polans A.S., Buczylko J., Crabb J., Palczewski K. J. Cell Biol. 112:981-989(1991). [3]”Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method.” Oshikawa M., Tsutsui C., Ikegami T., Fuchida Y., Matsubara M., Toyama S., Usami R., Ohtoko K., Kato S. Invest. Ophthalmol. Vis. Sci. 52:6662-6670(2011).

Additional information

Size

50μg, 100μg

Certificate of Analysis