STAT5a(Phospho-Tyr694) Antibody

$454.00

Cat. No.: 38741 Categories: ,

Description

Aliases

MGF; MPF; Mammary gland factor; STA5A, ; STAT5

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: P42229
NCBI Protein: NP_003143.2

Immunogen

Peptide sequence around phosphorylation site of tyrosine 694 (D-G-Y(p)-V-K) derived from Human STAT5A.

Raised In

Rabbit

Species Reactivity

Human Mouse Rat

Tested Applications

WB IHC Recommended dilution: Predicted MW: 90kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,

Background / Function

Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Tyr694

Additional information

Size

100?l

Certificate of Analysis