MGF; MPF; Mammary gland factor; STA5A, ; STAT5
NCBI Protein: NP_003143.2
Peptide sequence around phosphorylation site of tyrosine 694 (D-G-Y(p)-V-K) derived from Human STAT5A.
Human Mouse Rat
WB IHC Recommended dilution: Predicted MW: 90kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,
Background / Function
Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription.Gouilleux F, et al. (1994) EMBO J. 13: 4361-4369.Dentelli P, et al. (1999) J Immunol. 163: 2151-2159.Meinke A, et al. (1996) Mol Cell Biol. 16: 6937-6944.
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.