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sulA Antibody, HRP conjugated

$187.50$395.85

Description

Aliases

Cell division inhibitor SulA, sulA, sfiA, b0958, JW0941

 

Antibody Type

Polyclonal Antibody

 

Species

Escherichia coli

 

Uniprot ID

P0AFZ5

 

Immunogen

Recombinant Escherichia coli Cell division inhibitor SulA protein (1-169AA)

 

Raised In

Rabbit

 

Species Reactivity

Escherichia coli

 

Tested Applications

ELISA;Not yet tested in other applications.

 

Background / Function

Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. The effect of overexpression of SulA is neutralized by antitoxin CbeA (yeeU) (PubMed:22515815).

 

Isotype

IgG

 

Conjugate

HRP

 

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

 

Form

Liquid

 

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

 

Purity

>95%,Protein G purified

 

Additional information

Size

50μg, 100μg

Certificate of Analysis