USP6 Antibody, HRP conjugated

Aliases Ubiquitin carboxyl-terminal hydrolase 6, Deubiquitinating enzyme 6, Proto-oncogene TRE-2, Ubiquitin thioesterase 6, Ubiquitin-specific-processing protease 6, USP6, HRP1, TRE2 Antibody Type Polyclonal Species Human Uniprot ID P35125 Immunogen Recombinant Human Ubiquitin carboxyl-terminal hydrolase 6 protein (1122-1359AA) Raised In Rabbit Species Reactivity Human Tested Applications ELISA Background / Function Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation. Isotype IgG Conjugate HRP Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form Liquid Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze. Purity >95%,Protein G purified Modification Ubiquitin carboxyl-terminal hydrolase 6