Description
Aliases
APJ endogenous ligand APLN APEL
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
Q9ULZ1
Immunogen
Peptide
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, IHC;Recommended dilution:IHC:1:20-1:200
Background / Function
Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Literature
[1]”Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor.”Tatemoto K., Hosoya M., Habata Y., Fujii R., Kakegawa T., Zou M.-X., Kawamata Y., Fukusumi S., Hinuma S., Kitada C., Kurokawa T., Onda H., FuAdditional information
| Size | 50μg, 100μg |
|---|
