CTNNB1; CATNB; CTNB1; CTNNB;
NCBI Protein: NP_001091679.
Peptide sequence around phosphorylation site of serine 33 (L-D-S(p)-G-I) derived from Human b-Catenin.
Human Mouse Rat
WB IHC IF Recommended dilution: Predicted MW: 92kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,
Background / Function
Involved in the regulation of cell adhesion and in signal transduction through the Wnt pathway. Novak A, et al. (1998) Proc Natl Acad Sci U S A; 95(8): 4374-4379Marin O, et al. (2003) Proc Natl Acad Sci U S A; 100(18): 10193-10200Okamura H, et al. (2004) Mol Cell Biol; 24(10): 4184-4195Xing Y, et al. (2003) Genes Dev; 17(22): 2753-2764Barth AI, et al. (1999) Proc Natl Acad Sci U S A; 96(9): 4947-4952
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.