AH119; AP1; Jun A; c-Jun; p39
NCBI Protein: NP_002219.1
Peptide sequence around phosphorylation site of serine 243 (P-L-S(p)-P-I) derived from Human c-Jun.
Human Mouse Rat
WB IHC Recommended dilution: Predicted MW: 43kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100,
Background / Function
Transcription factor that recognizes and binds to the enhancer heptamer motif 5′-TGA[CG]TCA-3′.Boyle W J, et al. (1991) Cell. 64(3): 573-584.Binetruy B, et al. (1991) Nature. 351: 122-127.Smeal T, et al. (1991) Nature. 354:494-496.Derijard B, et al. (1994) Cell. 76:1025-1037.Kyriakis J M, et al. (1994) Nature. 369: 156-160.
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.