Caspase 10, Human Recombinant
Caspase-10 is an initiator caspase, highly homologous to Caspase-8, a relationship that extends to the death effector domains (DEDs) of their proforms. Caspase-10 was reported to activate early in TRAIL-induced apoptosis and was found in association with the DR4 (TRAIL-R1) receptor complex in a thyroid carcinoma line.
Synonyms: FLICE2, Mch4
Molecular Weight: 17KDa and 12 kDa
Source: E. coli.
Concentration: 100 U/µl
Formulation: Liquid, in 50mM HEPES, pH 7.4, 100mM NaCl, 0.1% CHAPS, 1mM EDTA, 10% glycerol, 10mM DTT
Specific Activity: One U=1pmol/min using Ac-IETD-pNA (200µM; Prod. No. ALX-260-045) as substrate at 30°C
Storage temp.: -80°C