Caspase 4, Human Recombinant
Caspase-4 (also known as Ich-4, ICErelII, TX) is a member of the caspase-family of cysteine proteases. Similar to other caspases, Caspase-4 exists in cells as an inactive proenzyme which is matured by proteolysis to yield large and small subunits. The active Caspase-4 is a heterotetrametric molecule consisting of two large and two small subunits. To date the mechanism of Caspase-4 activation and roles of Caspase-4 in apoptosis are poorly understood. The recombinant active human Caspase-4 was expressed in E. coli.
Synonyms: Caspase-4, CASP-4, ICE (rel)-II, Protease ICH-2, Protease TX
Gene Symbol: CASP4
Gene ID: 837
Source: E. coli.
Form: Lyophilized powder
Reconstitution Inst.: Reconstitute to 1 unit per µl in distilled H2O
Handling: Centrifuge the vial prior to opening
Storage temp.: -70°C