Caspase 5, Human Recombinant
Caspase-5 (also known as ICErelIII, TY) is a member of the caspase-family of cysteine proteases. Similar to other caspases, Caspase-5 exists in cells as an inactive proenzyme which is matured by proteolysis to yield large and small subunits. The active Caspase-5 is a heterotetrametric molecule consisting of two large and two small subunits. To date the mechanism of Caspase-5 activation and roles of Caspase-5 in apoptosis are poorly understood. The recombinant active human Caspase-5 was expressed in E. coli.
Synonyms: Caspase-5, CASP-5, ICE (rel)-III, Protease ICH-3, Protease TY
Gene Symbol: CASP5
Gene ID: 838
Source: E. coli.
Form: Lyophilized powder
Reconstitution Inst: Reconstitute to 1 unit per µl in PBS containing 15% glycerol
Handling: Centrifuge the vial prior to opening
Storage temp.: -70°C