Caspase 5, Human Recombinant

Description

Caspase 5, Human Recombinant

General description

Caspase-5 (also known as ICErelIII, TY) is a member of the caspase-family of cysteine proteases. Similar to other caspases, Caspase-5 exists in cells as an inactive proenzyme which is matured by proteolysis to yield large and small subunits. The active Caspase-5 is a heterotetrametric molecule consisting of two large and two small subunits. To date the mechanism of Caspase-5 activation and roles of Caspase-5 in apoptosis are poorly understood. The recombinant active human Caspase-5 was expressed in E. coli.

Synonyms:                       Caspase-5, CASP-5, ICE (rel)-III, Protease ICH-3, Protease TY

Gene Symbol:                  CASP5

Gene ID:                            838

Source:                              E. coli.

Form:                                 Lyophilized powder

Reconstitution Inst:        Reconstitute to 1 unit per µl in PBS containing 15% glycerol

Handling:                          Centrifuge the vial prior to opening

Storage temp.:                 -70°C

Additional information