Caspase-8 Substrate (Ac-IETD-pNA) [1mM], Colorimetric


Cat. No.: 10060 Categories: ,


Caspase-8 Substrate (Ac-IETD-pNA) [1mM], Colorimetric


General description

This product is a ready-to-use colorimetric substrate for FLICE/Caspase-8 and related caspases that recognize the amino acid sequence IETD. The sequence IETD is based on Caspase-8 cleavage site in CPP32/Caspase-3 proenzyme. FLICE and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate IETD-pNA, using a spectrophotometer or multi-well plate reader.


Synonyms:                       Ac-IETD-pNA, Caspase-8 Substrate, Colorimetric

Peptide Sequence:          Ac-Ile-Glu-Thr-Asp-pNA

Appearance:                     Liquid

Formulation:                    DMSO (4 mM)

Molecular Formula:        C₂₇H₃₈N₆O₁₂

Molecular Weight:           638.6

InChi Key:                         FHURKTIGZAIQGR-BQCLNCLCSA-N

PubChem CID:                 25108782

Handling:                          Protect from light and moisture

Storage temp.:                 -20°C


Additional information



Certificate of Analysis