SMPB (Succinimidyl 4-(p-maleimidophenyl)Butyrate)


Cat. No.: 10562 Categories: ,


General Description

SMPB is Succinimidyl 4-(p-maleimidophenyl)Butyrate, a heterobifunctional crosslinkers that contain N-hydroxysuccinimide (NHS) ester and maleimide reactive groups that permit covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at alkaline pH 7-9 to form amide bonds, while maleimides react with sulfhydryl groups at acidic pH 6.5-7.5 to form stable thioether bonds.


Molecular Weight:    356.33

Spacer Arm:               11.6Å


Features of SMPB:

1. Reactive groups: NHS ester and maleimide

2. Reactive towards: amino and sulfhydryl groups

3. Non-cleavable


Additional information


50 mg

Certificate of Analysis