Synapsin(phospho-Ser549) Antibody

$454.00

Cat. No.: 38867 Categories: ,

Description

Aliases

Syn-1; synapsin I;

Antibody Type

Polyclonal Antibody

Uniprot ID

Swiss-Prot: O88935
NCBI Protein: NP_038708.3

Immunogen

Peptide sequence around phosphorylation site of serine 549(P-A-S(p)-P-S)derived from Rat Synapsin

Raised In

Rabbit

Species Reactivity

Human Rat Mouse

Tested Applications

WB Recommended dilution: Predicted MW: 78kd, Western blotting: 1:500~1:1000

Background / Function

Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level Greengard, P. (1987) Mol Neurobiol 1, 81-119. Hosaka, M. et al. (1999) Neuron 24, 377-87.

Conjugate

Unconjugated

Storage Buffer

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form

liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Modification

Phospho-Ser549

Additional information

Size

100?l

Certificate of Analysis