Caspase-3, 7, 10 Inhibitor (Z-DEVD-FMK) [1mM]


Cat. No.: 10199 Category:


Caspase Inhibitors, Caspase 3, 7 Inhibitor, fluoromethyl ketone, FMK


General description

It is a synthetic peptide that irreversibly inhibits activity of DEVD-dependent caspases (e.g., Caspase-3 and Caspase-7) and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability, and the product can be used for both in vitro and in vivo studies. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).


Synonyms:                        Z-DEVD-FMK, Z-DEVD-fluoromethylketone, Caspase-3 inhibitor (fluoromethylketone)

Peptide Sequence:          Z-Asp (OMe)-Glu (OMe)-Val-Asp (OMe)-FMK

Appearance:                     Lyophilized solid

Molecular Formula:         C₃₀H₄₁FN₄O₁₂

Molecular Weight:           668.7

Solubility:                          DMSO (20 mM)

InChi Key:                         GBJVAVGBSGRRKN-JYEBCORGSA-N

PubChem CID:                 16760394

Handling:                          Protect from light and moisture

Storage temp.:                -20°C


Additional information


100 µl