Bcl2 Antibody

$210.00$377.00

Cat. No.: 40164 Categories: ,

Description

Aliases

Bcl2, Bcl-2

Antibody Type

Polyclonal Antibody

Species

Mouse

Uniprot ID

P10417

Immunogen

Recombinant mouse Apoptosis regulator Bcl-2 protein (5-205AA)

Raised In

Rabbit

Species Reactivity

Mouse

Tested Applications

ELISA, IHC;Recommended dilution:IHC:1:20-1:200

Background / Function

Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Others

Literature

[1] "Molecular analysis of mbcl-2: structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma."Negrini M., Silini E., Kozak C., Tsujimoto Y., Croce C.M.Cell 49:455-463(1987) [2] "Isolation

Additional information

Size

50μg, 100μg

Certificate of Analysis