GPR75 Antibody

$210.00$377.00

Cat. No.: 42097 Categories: ,

Description

Aliases

Probable G-protein coupled receptor 75, GPR75

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

O95800

Immunogen

Recombinant human Probable G-protein coupled receptor 75 protein (372-540AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA, WB, IHC, IF;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200, IF:1:50-1:200

Background / Function

G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Isotype

IgG

Conjugate

Unconjugated

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Additional information

Size

50μg, 100μg

Certificate of Analysis