Description
Aliases
Probable G-protein coupled receptor 75, GPR75
Antibody Type
Polyclonal Antibody
Species
Human
Uniprot ID
O95800
Immunogen
Recombinant human Probable G-protein coupled receptor 75 protein (372-540AA)
Raised In
Rabbit
Species Reactivity
Human
Tested Applications
ELISA, WB, IHC, IF;Recommended dilution:WB:1:500-2000, IHC:1:20-1:200, IF:1:50-1:200
Background / Function
G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.
Isotype
IgG
Conjugate
Unconjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Additional information
Size | 50μg, 100μg |
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