HMGCR Antibody, Biotin conjugated

Description

Aliases

HMGCR

Antibody Type

Polyclonal Antibody

Species

Human

Uniprot ID

P04035

Immunogen

Recombinant human 3-hydroxy-3-methylglutaryl-coenzyme A reductase protein (588-887AA)

Raised In

Rabbit

Species Reactivity

Human

Tested Applications

ELISA;Not yet tested in other applications.

Background / Function

Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

Isotype

IgG

Conjugate

Biotin

Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Purity

Caprylic Acid Ammonium Sulfate Precipitation purified

Research

Metabolism

Literature

[1] “Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation.” Luskey K.L., Stevens B.J. Biol. Chem. 260:10271-10277(1985) [2] “Human HMG-CoA reductase gene.”Nakajima

Additional information

Size	50μg, 100μg